Combo Test Kit for Creatine Kinase Isoenzyme / Myoglobin / Cardiac Troponin I

 

 

This cTnI/CK-MB/MYO Test Kit (TRFIA) is used in vitro to detect cardiac troponin I, creatine kinase isoenzyme, and myoglobin in human serum/plasma/whole blood.

The measurement of cardiac troponin I (cTnI) may help in the diagnosis of an acute myocardial infarction (AMI). Clinical investigations have shown that cardiac troponin I may be identified in the blood 4-6 hours after an AMI and can stay high for many days. Because of its myocardial specificity and sensitivity, cTnI may be utilized as a gold standard for diagnosing AMI. Creatine kinase isoenzyme (CK-MB) is widely used as a diagnostic marker of myocardial injury in the detection of acute myocardial infarction (AMI). Clinical studies have shown that CK-MB is released into blood circulation during myocardial injury and peaks within 12~24 hours and returns to normal level within 48~72 hours. Therefore, the detection of CK-MB has great clinical significance for the diagnosis of AMI. Myoglobin (abbreviated MYO) is an early indicator of myocardial necrosis. Myoglobin may be found in clinical tests within 1 hour after start and peaks in 45 hours. However, myoglobin levels increase in several situations, including skeletal muscle damage, skeletal muscle or neuromuscular dysfunction, cardiac shunt surgery, renal failure, and high-intensity physical activity. As a result, myoglobin elevation must be utilized as an auxiliary diagnosis of acute myocardial infarction (AMI) with other cardiac markers, electrocardiogram (ECG), clinical symptoms and signs, and so on. Chemiluminescence, enzyme immunoassay, fluorescence immunoassay, and colloidal gold assay are now used to detect the levels of cTnI, CK-MB, and MYO in blood samples.

 

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1. "Golden Standard" to diagnose myocardial infarction (MI)
2. Assess infarct size and ACS risks
3. Diagnose reinfarction or infarct extension
4. Diagnosis of myocardial injury in the perioperative period and perinatal period
5. As myocardial infarction (AMI) early detection indicator, highly sensitive
6. Diagnose reinfarction or infarct extension
7. Determine myocardial reperfusion

 

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1. Advanced: time-resolved fluorescence immunoassay quantitative chromatography
2. Quantitative: quantitative detection of cardiac troponin I (cTnI), creatine kinase (CK-MB) and myoblobin (MYO)
3. Accurate: well correlated with imported chemiluminescence reagent (r> 0.975)
4. High sensitivity: lower detection limit <0.05 ng/mL (cTnI) , <0.25 ng/mL (CK-MB) and <1.0 ng/mL (MYO)
5. Simple: simple operation, suitable for bedside detection
6. Widely applicable : outpatient laboratory, emergency laboratory, medical center, cardiology, ICU, and etc

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